Mar 1

The Parkinsons Drug Trial A Miracle Cure S01E01 HDTV x264-PLUTONiUM

Filmed over six years, 42 people with Parkinson’s take part in a groundbreaking medical trial. Can the results give hope to 10 million Parkinson’s sufferers worldwide?

Season 1, Episode 1
In this moving first episode, cameras follow Professor Gill performing surgery on all the volunteers to implant the device he has designed that enables delivery of GDNF to a deep part of the brain. The device comprises four catheters placed in the putamen (a part of the brain key in Parkinson’s) that link to a port embedded in the side of the skull through which GDNF can be infused monthly.

The surgery and infusions that follow are medical firsts, offering a whole new way of delivering drugs to the brain. It leads to Pfizer, the world’s biggest pharmaceutical company, investing in GDNF and the Bristol delivery system part-way through the trial.

Tom Isaacs, 44, from Hertfordshire, is one of the trial’s most severely-affected volunteers, diagnosed with Parkinson’s aged 27. Tom says, ‘It is with you every single second of every single day’.

After five years of one of the world’s most ambitious medical trials, we find out whether the drug is the breakthrough the world has been waiting for.

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